Oct 18, 2017 · Estimates based on healing rates for a variety of conditions. Recommended reading: McDonagh MS et al. (See references). Dosing: Healing of erosive esophagitis: Oral: Initial: 20-40 mg once daily for 4-8 weeks. if incomplete healing, may continue for an additional 4-8 weeks. Maintenance: 20 mg once daily.

Note: Lansoprazole is IWK formulary PPI. Chart does not include all available PPIs.

** Olmesartan (Benicar) lowers the DBP & SBP approximately 3-4 mmHg more than the corresponding dose of the other ARBs. Lowest dose of ARB’s are often for patients with volume or salt depletion.

• IV PPI CI should be used for no longer than 72 hours (i.e., patients need to be converted to PO or NG admini- stration as soon as possible using esomeprazole 40 mg PO or lansoprazole SoluTab™ 30 mg NG once daily).

We used omeprazole equivalency and the surrogate biomarker, percentage time pH > 4 over a 24-hour period (pH4time), to compare PPI effectiveness for different PPIs given once, twice, or 3 times daily.

We used omeprazole equivalency and the surrogate biomarker, percentage time pH 4 over a 24-hour period (pH4time), to compare PPI effectiveness for different PPIs given once, twice, or 3 times daily.

Calculation of equivalent doses of PPI : Active agent 1: Active agent 2: Drug names

We conclude that PPIs can be used interchangeably based on potency. Using twice-daily PPIs is more effective in increasing efficacy increasing once-daily PPI dosage. Omeprazole and lansoprazole (30 mg) and 20 mg of esomeprazole rabeprazole are functionally equivalent.

All new medication orders for PPIs (e.g., lansoprazole, omeprazole, pantoprazole, and rabeprazole) ® ® for oral (PO) and intravenous (IV) administration, will be automatically converted to esomeprazole.

Mar 23, 2023 · Different guidelines have notable differences between equivalency dosing of proton pump inhibitors (PPI), resulting in confusion and a lack of confidence between medical professionals recommending one PPI over another.