The cells in the respiratory epithelium are of five main types: a) ciliated cells, b) goblet cells, c) brush cells, d) airway basal cells, and e) small granule cells (NDES) [6] Goblet cells become …

Study the biology of airway epithelial cell “stemness,” and define the complex signaling pathways that direct airway epithelial stem/progenitor cells to differentiate to distinct epithelial cell types.

In a healthy state (blue arrows), basal cells are the principal stem cells of the airway, facilitating epithelial regeneration. Club cells secrete the anti-inflammatory protein...

Jan 13, 2021 · In addition to its structural attributes that provide effective mucociliary clearance of the lower airspace, the airway epithelium is an immunologically active barrier surface that …

May 1, 2023 · In the most proximal airway, hyaline cartilage rings support the larger respiratory passages, namely, the trachea and bronchi, to facilitate the passage of air. Three major cell …

Aug 1, 2018 · Here we perform single-cell profiling of human bronchial epithelial cells and mouse tracheal epithelial cells to obtain a comprehensive census of cell types in the conducting …

Leveraging single-cell RNA-sequencing data in combination with known cell type–specific markers, we developed panels of antibodies to characterize and isolate the major airway …

In this review, we discuss airway basal cells in respiratory diseases, the communication network between airway basal cells and tissue-resident and/or recruited immune cells, and how basal …

There are a number of distinct types of epithelial cells within the airways, of which columnar ciliated and goblet cells are the most prominent. Other subtypes include serous, basal, Clara, …

Oct 26, 2024 · Neuroendocrine cells are specialized components of the respiratory epithelium, characterized by their ability to secrete bioactive molecules. These cells are strategically …