Paramyxoviruses - Medical Microbiology - NCBI Bookshelf
These viruses first infect the ciliated epithelial cells of the nose and throat. Infection may extend to the paranasal sinuses, the middle ear, and occasionally to the lower respiratory tract. Progeny viruses spread among cells both extracellularly and intracellularly.
Paramyxoviridae - Wikipedia
Paramyxoviridae (from Greek para- “by the side of” and myxa “ mucus ”) is a family of negative-strand RNA viruses in the order Mononegavirales. [1][2] Vertebrates serve as natural hosts. [3] . Diseases associated with this family include measles, mumps, and respiratory tract infections. [4] .
Paramyxovirus - StatPearls - NCBI Bookshelf
Jul 10, 2023 · The Paramyxoviridae is a family of single-stranded RNA viruses known to cause different types of infections in vertebrates. Examples of these infections in humans include the measles virus, mumps virus, parainfluenza virus, and respiratory syncytial virus (RSV).
Paramyxoviruses: Respiratory Syncytial Virus and Human …
Human metapneumovirus (HMPV, MPV) is a paramyxovirus isolated in 2001 from Dutch children with acute respiratory infection (ARI). Epidemiologic studies have since confirmed that MPV is a leading cause of upper and lower respiratory infection in children and adults worldwide.
Paramyxoviruses: Pathogenesis, Vaccines, Antivirals, and …
Oct 18, 2023 · In this review, the general life cycle, taxonomic relationships, and viral pathogenesis are described for paramyxoviruses that cause both systemic and respiratory system–restricted infections. Next, key gaps in critical areas are presented, following detailed conversations with subject matter experts and based on the current literature.
Paramyxovirus Infection - an overview | ScienceDirect Topics
Paramyxovirus infection typically begins in the respiratory tract and may remain at that site (e.g., HRSV and HPIV) or may spread to secondary sites (e.g., lymphoid and endothelial tissues for MeV, or the parotid gland, CNS and endothelial tissues for MuV). In general, paramyxovirus infections are limited by, and eliminated by, host immunity.
Paramyxovirus | Respiratory, Mumps & Measles | Britannica
paramyxovirus, any virus belonging to the family Paramyxoviridae. Paramyxoviruses have enveloped virions (virus particles) varying in size from 150 to 200 nm (1 nm = 10 −9 metre) in diameter.
Chapter 6: Paramyxovirus Entry - PMC - PubMed Central (PMC)
Like all enveloped viruses, paramyxoviruses must fuse their membrane with that of a receptive host cell as a prerequisite for viral entry and infection. Unlike most other enveloped viruses, the vast majority of paramyxoviruses contain two distinct membrane-anchored glycoproteins to mediate the attachment, membrane fusion and particle entry ...
Paramyxoviridae - Stanford University
Mar 4, 1998 · Severe RSV infection is characterized by a pronounced cough and wheezing which eventually deveops into dyspnea and a high respiratory rate and hypoxemia. Death occur in about 1% of infants who develop serious illness.
Paramyxovirus Activation and Inhibition of Innate Immune …
Paramyxoviruses are potent activators of extracellular complement pathways, a first line of defense that viruses must face during natural infections. We discuss mechanisms by which these viruses activate and combat complement to delay neutralization.
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