Drivers traveling on Interstate 64 in southern Illinois could be impacted by a broken-down semi-trailer blocking the road.

Valerie Mahaffey, whose stage, film and television work ranged from Shakespeare to the hit 1990s series “Northern Exposure,” died at age 71 after a battle with cancer.

The Cape Girardeau County Historical Society will offer a bus tour of early settlements in the county on Saturday, June 28 at 9 a.m.

RIPLEY COUNTY, Mo. (KFVS) - A man died in a single-vehicle crash overnight in Ripley County, Missouri. According to the Mo.

Be sure to grab your sunglasses and a hat if you plan on being outdoors. Looking ahead, Sunday will offer more of the same ...

After tornadoes downed multiple trees at the Saint Louis Zoo two weeks ago, the zoo staff decided to make the best of the situation.

Playing post-season games in the Magnolia State is proving to be a lucky charm for Murray State’s baseball team.

The Perry County, Missouri sheriff’s department says representatives from the Federal Emergency Management Agency will be available at the Park Center Farmer’s Market.

Tens of thousands of Missourians could lose all or some of their food and health assistance if President Trump’s budget bill is passed.

Century Casinos, Inc. entered into an agreement with BetMGM to offer Missouri sports betters a mobile sports betting app.

It’s been exactly two weeks since an EF3 tornado struck a heartland neighborhood, and volunteer groups are stepping up to help pick up the pieces left from the destruction.

McCracken County investigators say one man has been charged and another is wanted after an investigation that started with a ...