Improved heart function with sacubitril/valsartan was linked to enhanced ventricular-arterial coupling and cardiac efficiency ...

The agency’s own expert said that “various pre-specified and post-hoc analyses suggest that sacubitril/valsartan compared to valsartan reduces HF events” in HFpEF, and of course Entresto’s ...

The firm already markets recently-approved Entresto (sacubitril+valsartan) to treat heart failure, and diabetes drug Galvus (vildagliptin) through its cardio-metabolic division, and is looking to ...