Pancreatic cancer is a leading cause of cancer-related death, with a five-year survival rate of 13%. The high mortality is ...

Researchers at Hopkins have made strides in pancreatic cancer research, both in understanding age-related differences in ...

Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

Early-onset CRC (EO-CRC) was associated with Flavonifractor plautii and increased bile acid, tryptophan, and choline ...

A recent study identified biological pathways common to cancer-related cognitive impairment (CRCI) and anxiety, based on gene expression data for patients with a variety of cancer types.

Studying mice with cancer-linked cachexia, a condition typical of the disease that leads to muscle wasting and weight loss, they discovered a previously unrecognized pathway in the brain.

ROS activated the p53 signaling pathway and promoted the nuclear translocation ... Hdy-7 showed comparable cytotoxicity against five cancer cell lines, including Taxol resistant A549 Taxol cells.

1Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. 2The Melanoma and Skin Cancer Center, The Pennsylvania State University College of Medicine, ...

Mol Cancer Ther (2025) 24 (4): 497–510 ... The trend of MDM2 degradation observed with KT-253 treatments corresponds to the activation of the p53 pathway, as evidenced by an upregulation of proteomic ...

Tang Center for Herbal Medicine Research and Department of Anesthesia & Critical Care, Pritzker School of Medicine, University of Chicago, Chicago IL 60637, USA Tang Center for Herbal Medicine ...