ROS activated the p53 signaling pathway and promoted the nuclear translocation ... Hdy-7 showed comparable cytotoxicity against five cancer cell lines, including Taxol resistant A549 Taxol cells.

Early-onset CRC (EO-CRC) was associated with Flavonifractor plautii and increased bile acid, tryptophan, and choline ...

Overproduced Wnt5a promotes the EMT of cancer cells via STAT3 signaling pathway. PCs-derived LIF inhibits tumor angiogenesis via Src/P53 signaling pathway. PCs are crucial components that regulate the ...

[45] Suh (2002) Cell signaling in aging and apoptosis ... the molecular pathways. Urol Oncol, 6, 620-7. [56] Feng, Hu, Rajagopal, and Levine (2008) The tumor suppressor p53: cancer and aging. Cell ...

Pancreatic cancer is a leading cause of cancer-related death, with a five-year survival rate of 13%. The high mortality is ...

Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that ...

Ten pediatric cancer treatment sites previously implemented site-specific symptom management care pathways for 15 symptoms, which were based upon clinical practice guidelines (CPGs). The primary ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...