This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

Parabilis Medicines (formerly Fog Pharmaceuticals), a clinical-stage biopharmaceutical company committed to creating extraordinary medicines for people living with cancer, is presenting preclinical ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Conclusions: These findings provide new insights into the molecular underpinnings of AR-mediated radioresistance and identify MAPK and MYC pathways as potential therapeutic targets to enhance ...

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Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for ...

The pathway to national elections, whether in December 2025 or in 2026, is not likely to be so smooth. Whenever the election campaign hits the streets, we will get a sense of how far the attempt ...

Instead of a fragmented patient journey, the Longitudinal Patient Experience provides structured pathways for care. For more than a decade, CMS has aimed to improve patient outcomes and reduce the ...

She was supposed to put a fresh face on the DeSantis brand, elevating the meager political skills of her whiny, vindictive marital partner — who is term-limited but not emotionally ready to cede ...