Week 6 starts with a Thursday Night Football matchup between two teams facing a serious gut check: the 49ers vs. Seattle ...

NFL MVP award odds for this season favor Patrick Mahomes, C.J. Stroud, Lamar Jackson and Josh Allen, but Jayden Daniels and ...

The Bills' loss to the Texans was painful, but Sean McDermott's game management wasn't felonious. In fact, his demeanor was ...

Jalen Tolbert and Darnell Mooney are among UPI senior sports writer Alex Butler's five must-start wide receivers for Week 6 ...

The Bengals have the most efficient offense since the arrival of Joe Burrow, who leads the NFL in touchdown passes and has ...

Houston Texans linebacker Azeez Al-Shaair nearly picks off a deep pass from Buffalo Bills quarterback Josh Allena that was ...

The performances of Jacksonville Jaguars wide receiver Brian Thomas Jr. (23.2), Chicago Bears quarterback Caleb Williams ...

Here's everything you need to know for Week 5 NFL games. Which teams will win? Who are the X factors, and which storylines ...

Cincinnati Bengals running back Chase Brown makes it pylon for 4-yard TD. Miami Dolphins quarterback Tyler Huntley strikes wide receiver Tyreek Hill 16 yards downfield to give the Miami Dolphins ...

An impressive road win for the Cardinals over the 49ers has Arizona climbing the ranks in our Week 6 NFL Power Rankings. Even though Kyler Murray and Marvin Harrison Jr. weren’t on the same page for ...

Halfway through the NFL Week 5 Sunday slate it looked like underdogs were finally going to take a back seat. Then, out of ...

Buffalo Bills quarterback Josh Allen and Miami Dolphins running back De'Von Achane were among the NFL players injured in Week ...