As the brain's most abundant excitatory neurotransmitter, glutamate facilitates our ability to learn, form memories, and regulate our mood. Yet this powerful neurotransmitter can become both ...

A new study shows that when energy is depleted—such as during a stroke—neurons begin releasing glutamate in abnormal, self-amplifying bursts that can damage nerve cells.

Our brain requires a constant supply of energy. A disrupted energy supply, as, for instance, caused by a stroke, can have ...

Glutamate, an essential neurotransmitter responsible for regulating functions such as mood and memory, can also encourage the toxic buildup of tau proteins, which are known to contribute to ...

Chronic pain triggers systemic inflammation and neural disruption, increasing depression risk—even in those without prior ...

Long-term depression (LTD) encompasses a family of synaptic plasticity mechanisms that can be triggered by the synaptic or pharmacological activation of glutamate receptors — in particular ...

The authors write that, in light of their results, nutritional glutamate supplementation can effectively promote liver regeneration and benefit patients with severe and chronic liver damage ...

It is a process that is triggered very quickly, just a few minutes after acute liver damage occurs, with the amino acid glutamate playing a key role. The authors write in Nature that, in light of ...