or sometimes by switching off the gene altogether to see what happens if it doesn’t work (these are called knockout mice, and they’re a staple of medical lab research). In 2013, researchers in ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Trump misstated $8 million spent on transgender mice, sparking debate on transgenic research and its importance in science.

Colossal Biosciences leaders say the fluffy, golden-haired mice help validate their technique to “de-extinct” species, but ...

However, the role of the Nwd1 gene in SERCA2 activity and the ... The team created an Nwd1 knockout (Nwd1 −/−) mice model ...

A research team led by Prof. Zhang Xin from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has revealed how magnetic properties in mice vary under different physiological ...

The team then edited the mouse genome using a streamlined strategy that combined three editing technologies: RNP-mediated knockout ... to modify seven genes. The gene editing resulted in mice ...

The mice were created by Colossal Biosciences, which edits DNA for species conservation, and has been working to bring back the woolly mammoth since 2021.

On Tuesday, the team behind the plan to bring mammoth-like animals back to the tundra announced the creation of what it is ...

A research team led by Prof. ZHANG Xin from High Magnetic Field laboratory, the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, has revealed how magnetic properties vary in ...

By replacing the defective gene associated with Dravet syndrome in mice, scientists successfully alleviated symptoms without ...

A one-time injection of a novel gene therapy was able to save mice and a newborn calf from succumbing to maple syrup urine disease (MSUD), suggesting the approach could one day be used to treat ...