RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

Then the RNA binding protein communicates to the splicing machinery ... Alternative splicing plays a pivotal role in defining cell phenotypes and physiology in multicellular eukaryotes, often ...

To ensure that RNA polymerase II copies the correct genes at the correct time ... Collectively these PTMs and recruited protein factors constitute the ‘CTD Code’ for eukaryotic transcription ...

Since the cellular enzyme RNA polymerase II (RNAP-II) is responsible for the transcription ... a TATT box motif is frequently found in the position where the consensus TATA box of eukaryotic promoters ...

Eukaryotic genomes contain a variety of structured patterns: repetitive elements, binding sites of DNA and RNA associated proteins, splice sites, and so on. Often, these structured patterns can be ...

These messenger RNAs are then used as templates for protein production. In animals, plants and other eukaryotic organisms, an enzyme called RNA polymerase II is responsible for making messenger RNA ...