A new scientific review published in Neuropharmacology explores how the environment interacts with brain biology in shaping personality disorders. By examining molecular, neurochemical, and metabolic ...

By performing tests on mice with modified MEKs, the team discerned that anthrax killed its host by disrupting two important pathways: ERK, which participates in cellular division, and p38, which is ...

The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...

Surprisingly, this process does not rely on reactivating the BRAF-ERK pathway, which is the usual resistance mechanism. Using cutting-edge mass spectrometry-based phosphoproteomics and deep ...

Surprisingly, this process does not rely on reactivating the BRAF-ERK pathway, which is the usual resistance mechanism. Using cutting-edge mass spectrometry-based phosphoproteomics and deep ...