Title: QTX3544, a potent and selective G12V-preferring KRAS inhibitor, synergizes with EGFR inhibitors for enhanced anti-tumor activity Date and Time: Wednesday, April 30, 2025; 9:00 AM - 12:00 PM ...

A new review was published in , Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." ...

Scabies commonly presents as a red rash with small bumps that often form a line. Other symptoms of scabies include itching, blistering, and scaling. According to the World Health Organization (WHO), ...

Several phase II–III studies have shown that the EGFR-targeting monoclonal antibody, cetuximab, offers clinical benefit for patients with SCCHN. Cetuximab monotherapy is active in patients whose ...

Clin Colorectal Cancer. 2009;8(1):15-21. The primary challenge now faced is integration of this knowledge into current clinical practice. Well-designed studies, with consistent tissue sources and ...

NEW YORK – Up to 40 percent of patients with KRAS G12C mutations driving their colorectal and pancreatic cancer also have tumor alterations associated with primary resistance to KRAS G12C inhibitors, ...

Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancer TA61 27 May 2003 27 May 2003 Guidance on the use of drugs for early thrombolysis in the treatment of acute ...

BRAFTOVI in combination with cetuximab and mFOLFOX6 showed statistically significant and clinically meaningful improvement in progression-free survival and overall survival in patients with ...

including FDA approval for agents like the EGFR-targeting monoclonal antibody cetuximab for K-RAS wild-type, EGFR-mutant HNSCC treatment. Non-coding RNAs (ncRNAs), owing to their enhanced stability in ...

This process isn't perfect, and errors can occur that affect genes within the chromosomes. Mutations in many different genes can be found in AML cells, but larger changes in one or more chromosomes ...

This paper challenges a fundamental view concerning why males of most animals have a higher germline mutation rate than females. Evidence is provided to show that it is not simply the fact that males ...