Model of cell cycle regulation and genome integrity protection by CHK1 in early mouse embryos. In wild‐type mouse embryous, active CHK1 (shown in purple) restrains CDK1 activity (gray) by promoting ...

An international research team led by the IPK Leibniz Institute has uncovered the molecular mechanisms governing the ...

Capricor's DMD therapy Deramiocel is under FDA Priority Review with no major issues flagged; PDUFA date set for August 31, ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the ...

Disruptions in circadian rhythms contribute to tumor initiation and progression through multiple mechanisms. These include metabolic reprogramming, alterations in cell cycle regulation, and ...

During organismal development, differential regulation of the cell cycle is critical to many cell biological processes, including cell migration, cell fate specification and differentiation. While the ...

The following is a summary of “Patient iPSC-derived neural progenitor cells display aberrant cell cycle control, p53, and DNA damage response protein expression in schizophrenia,” published in the ...

After losing volume between morning and evening, the brain resets overnight, starting the cycle again, the research shows. The study involved scanning a 26-year-old's brain 40 times in 30 days.

Later in each cycle, high CCO activity inhibits centrosome growth by suppressing the centrosomal recruitment and/or maintenance of centrosome proteins. Thus, in fly embryos, mitotic centrosome size ...

Dr Claudio Alfieri’s group is researching the structure and molecular function of the Muv-B complexes in regulating cell cycle-dependent transcription. Our group investigates the molecular mechanisms ...

To investigate the cell-cycle dependency of focal adhesion distribution and magnitude, Jones et al. investigated the role of cyclin‐dependent kinases (CDKs) in the regulation of adhesion dynamics.

This work was supported by the Fred Hutch/University of Washington Cancer Consortium, the Howard Hughes Medical Institute and the Helen Hay Whitney Foundation. Fred Hutch/UW Cancer Consortium member ...