San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

Now that the Cardinals' 2024 season has come to an end, we wanted to get some feedback from the fans as to how the team did.

Check out Kyler Murray's postgame interview after the Arizona Cardinals defeated the San Francisco 49ers in the last game of the regular season.

From Phoenix breaking a daily heat record to new Arizona laws that went into effect, here are some of the Valley's top news stories from Jan. 3-5.

Things just got a lot quieter around Montlake with University of Washington senior starting cornerback Thaddeus Dixon indicating on Sunday he will enter the tra ...

Watch highlights from the Week 18 matchup between the Kansas City Chiefs and the Denver Broncos during the 2024 NFL season.

Watch highlights from the Week 18 matchup between the Los Angeles Chargers and the Las Vegas Raiders during the 2024 NFL season.

The San Francisco 49ers lost to the Arizona Cardinals on Sunday to put a stamp on what was one of the worst seasons of the Kyle Shanahan era. By falling to 6-11 on the year, the 49ers did secure the ...

A man’s Waymo ride to the Sky Harbor International Airport took an unexpected turn when his autonomous vehicle got stuck circling a roundabout in a parking lot for several minutes.

The Arizona Cardinals and San Francisco 49ers entered the season final both struggling, Arizona having lost five of six and ...

Finally, the 2024 nightmare season for the San Francisco 49ers is over with. It ends in a blowout 47-24 loss to the Arizona ...