In a study published in Angewandte Chemie International Edition, a research team integrated activity-based protein profiling ...

By modulating the acetylation status of histones (e.g., H3K9 ... transcription factor is the most well-known mechanism employed by hypoxic cells in this hostile microenvironment. Notably, there is a ...

In addition, various drugs can also be used to treat pulmonary hypertension by modifying acetylation modifications. However, further research is needed on the specific mechanism and effect of ...