Arizona Cardinals' running back Michael Carter outraces the entire San Francisco 49ers defense on a 4-yard touchdown run to extends the Cardinals' lead to 33-24.

The San Francisco 49ers suffered a frustrating 29-17 loss to the Miami Dolphins at Hard Rock Stadium, as penalties undermined their chances to secure a critical win in the playoff race.

The San Francisco 49ers hosted their annual Hope for the ... and children were entertained with coloring books, board games and stickers. The event was made possible through the generosity of ...

The San Francisco 49ers suspended De'Vondre Campbell three games after the linebacker refused to enter the game against the Los Angeles Rams on Thursday, likely ending his time with the team.

It's been a disappointing season for both the San Francisco 49ers and Miami Dolphins. Each team came into the year with playoff expectations, but heading into Week 16, both teams have been all but ...

SANTA CLARA, Calif. -- For 60 fleeting minutes last Thursday night, San Francisco 49ers cornerback Deommodore Lenoir finally felt like he and his defensive teammates were back to their formerly ...

Well this isn't good. 49ers rookie Isaac Guerendo is nursing a new injury. Kyle Shanahan revealed Guerendo was held out of Wednesday's practice with a hamstring injury. He sustained the injury in ...

Pro Football Hall of Famer Jerry Rice called out San Francisco 49ers star Deebo Samuel for his crucial mistakes in the team’s 12-6 loss to the Los Angeles Rams last week. Samuel had three ...

The San Francisco 49ers suspended linebacker De'Vondre Campbell for the rest of the regular season Monday after he refused to enter a game after losing his starting job. The news came four days ...

SANTA CLARA – De’Vondre Campbell’s expulsion from the 49ers has come via an unpaid suspension for their final three games. That discipline was announced Monday in a two-line statement from ...

Is doubt beginning to set in for the San Francisco 49ers about their starting quarterback? Ever since he took over as a seventh-round rookie in the middle of the 2022 playoff push, Brock Purdy has ...