Larger studies looking at the benefits and harms of anti-TNF compared with conventional treatment for children with active Crohn's disease are needed. Among the important outcomes to be included are ...

Due to a lack of robust evidence, we could not determine the benefits and unwanted effects of hospital networks (organised trauma systems) or individual hospitals (designated trauma centres) that are ...

Large studies are needed to see if targeted therapies work in the different types of IIM. As IIM is rare, this would best be done by many centres working together internationally.

We found nine studies involving a total of 689 women with stress urinary incontinence. Nine studies compared vaginal lasers to either sham or lubricant, and one study compared vaginal lasers to ...

- Corticosteroids may decrease transient inflammatory reaction events associated with antibiotic treatment of leptospirosis infection, although the certainty of this evidence is very uncertain.

Palivizumab, when given through the veins or into a muscle (systemically), reduces hospitalisations due to respiratory syncytial virus (RSV) and reduces respiratory problems later on (chest wheezing), ...

Transcranial laser therapy (low-level light therapy applied to the head) does not reduce the number of people who die or have moderate to severe disability at 90 days after ischaemic stroke (where ...

A variety of manual therapies with similar postulated biologic mechanisms of action are commonly used to treat patients with asthma. Manual therapy practitioners are also varied, including ...

Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds, however, there is a lack of clarity regarding the evidence for their ...

Shigella dysentery is a relatively common illness and occasionally causes death, worldwide. Mild symptoms are self-limiting but in more severe cases, antibiotics are recommended for cure and ...

Review question We reviewed the evidence for the effectiveness and safety of antipsychotics for treatment of delirium in hospitalised patients, not including those in intensive care units (specialised ...

Five trials compared interventions for maintaining soft tissue health around implants and a further six trials compared interventions to recover soft tissue health where there was evidence of ...