Objective To determine whether any children in the UK had variant Creutzfeldt-Jakob disease (vCJD). Design This active ...

Introduction Trauma is the leading cause of death in children over 1 year of age in the UK. However, individual prehospital clinicians only encounter paediatric trauma patients rarely. This study ...

Background: Current best practice for treating acute severe pain in children is to administer intravenous or intranasal opioid. Intranasal diamorphine offers less traumatic analgesia than the ...

1 Department of Paediatric Respiratory Medicine, Great Ormond Street Hospital, London, UK 2 Department of Paediatric Otolaryngology, Great Ormond Street Hospital, London, UK Correspondence to Yogesh ...

OBJECTIVE To estimate physical activity energy expenditure (AEE) in groups of free living infants in the first year of life. DESIGN Mixed longitudinal study of 124 healthy infants, using 232 ...

Correspondence to Dr Amy Jane Stevens, Health Education England Yorkshire and the Humber, Leeds LS2 9JT, UK; amyjanestevens{at}doctors.org.uk The numbers of people forcibly displaced from their homes ...

Base deficit is a parameter often used to guide further treatment in acidotic children and is taken as a measure of how “sick” they are. Five children with septic shock are presented who had ...

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1 Northern Genetics Service, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK 2 Department of Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, UK ...

AIM To describe the clinical phenotype in infants with ARC syndrome, the association of arthrogryposis, renal tubular acidosis, and cholestasis. METHODS The medical records for six patients with ARC ...

Introduction Paracetamol is a readily available antipyretic and analgesic, widely used to treat mild to moderate pain. Unintentional overdosing in neonates occurs, but so far only single case reports ...