Introduction This systematic review aims to collate evidence of the causes of genital bleeding, other than child sexual abuse ...

Objective To determine the safety of ciprofloxacin in paediatric patients in relation to arthropathy, any other adverse events (AEs) and drug interactions. Methods A systematic search of MEDLINE, ...

Correspondence to: Prof. M Levin, Department of Paediatrics, Faculty of Medicine, Imperial College of Science, Technology & Medicine, Norfolk Place, London W2 1PG, UK; m.levin{at}ic.ac.uk Neisseria ...

Rationale Studies suggest that increased breastfeeding rates can provide substantial financial savings, but the scale of such savings in the UK is not known. Objective To calculate potential cost ...

Correspondence to Dr Chandra Sekhar Devulapalli, Medical Advisor Service, Norwegian Labour and Welfare Administration (NAV), Work and Benefits Kristiania, Oslo NO-0653, Norway; chandev{at}gmail.com An ...

Aims There is an increasing interest in prevention and population health following the publication of the NHS Long-Term Plan and Advancing Our Health, Prevention in the 2020’s. This paper examines the ...

BACKGROUND Overweight children become obese adults who are prone to develop the “metabolic syndrome” and premature coronary arterial disease (CAD). AIMS To assess whether sex hormone binding globulin ...

1 Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China 2 Centre for Clinical Trials and Epidemiological Research, The Chinese University of ...

Importance Children with neurodevelopmental disorders have a higher prevalence of sleep disturbances. Currently there is variation in the use of melatonin; hence, an up-to-date systematic review is ...

Aims To determine the effects of vitamin D supplementation on diverse health outcomes in vitamin D-deficient schoolchildren. Methods We performed a phase 3 randomised placebo-controlled clinical trial ...

Aims: To evaluate ibuprofen population pharmacokinetics in a large series of data collected in children with cystic fibrosis (CF) treated with high doses of ibuprofen (59 patients; 2–18 years), and to ...

Objectives To review the effects and safety of high-flow nasal cannula (HFNC) for bronchiolitis. Methods Six electronic databases including PubMed, EMBASE, Cochrane Central Register of Controlled ...