Analyzing Thursday’s San Francisco 49ers at Seattle Seahawks odds and lines, with expert NFL picks and predictions.

Talanoa Hufanga is likely to end up on Injured Reserve soon. He suffered torn ligaments in his wrist in the San Francisco ...

The San Francisco 49ers' rushing attack presents a big test for the Seattle Seahawks and their struggling defense.

After leading the Arizona Cardinals by 13 at halftime, the 49ers failed to score in the final 30 minutes while the Cardinals ...

Mike Macdonald shut down the San Francisco 49ers last season, and now looks to do the same with the Seattle Seahawks.

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San Francisco veteran kicker Jake Moody suffered a high right ankle sprain while attempting to make a tackle on a kick return ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

Two weeks after faltering on the road to the Los Angeles Rams, the 49ers blew another 10-point lead and exited with a 24-23 ...

Chad Ryland didn't have a job just a week ago, but he kicked three field goals for the Cardinals, including the game winner ...