1 A hallmark of RA pathology is synovitis, causing the synovium to thicken and form a pannus that invades cartilage and bone, driven by pathogenic transformation and proliferation of fibroblasts with ...

Conclusion Subclinical inflammation of the synovium does not coincide with the appearance ... None of these subjects showed inflammatory or degenerative joint pathology upon physical examination, ...

The nerve growth factor also drives neoinnervation in the synovium and subchondral bone (14 ... concomitant diseases were well controlled, and clinical pathology results (blood and urine) were ...

In other words, the lesion creates its own signal; if there is no signal, there is no pathology. Bone erosions and cartilage ... in order to define the surrounding synovium and quantify inflammation ...

But to understand what is really happening, we need to move beyond politics into the uncharted territory of pathology. Trump’s demagoguery is in the service of something far darker than the mere ...

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed ...

Mar. 25, 2025 — A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, according to researchers. If the drug proves viable for human ...

Conclusions These data demonstrate that PD-1 hi Tph cells are present in early rheumatoid arthritis, but not osteoarthritis synovium, and therefore may provide a target for treatment of patients with ...

Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes synovial joint inflammation as well as bone destruction and erosion, typically characterized by joint pain, swelling, and ...

Clinical and Radiographic Outcomes of Four Different Treatment Strategies in Patients With Early Rheumatoid Arthritis (the Best Study): A Randomized, Controlled Trialfrom Arthritis & Rheumatism ...