These insights from researchers could have major implications for diseases like cancer, where gene expression goes awry.

Scientists at the Icahn School of Medicine at Mount Sinai have made an exciting discovery about how human cells make RNA, a molecule that carries important instructions inside our bodies.

The designed RSV F protein, which was purified utilizing the AKTA pure™ chromatography system, underwent confirmation through ... which contained the T7 RNA polymerase promoter and terminator. After ...

mRNAs were transcribed using T7 RNA polymerase (T7 RNA Transcription Enzyme Mix ... which may be attributed to the influence of sequence length on molecular expression. Notably, combined immunization ...

Fred Hutch and MSK researchers showed that tumors driven by hiccups in RNA processing can't hid from the immune system. In ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

Protein yield and ease of purification are two important criteria in choosing a system for the expression/ purification of recombinant proteins. The IMPACT (Intein Mediated Purification with an ...

Human cells have a complex DNA repair system involving over 500 crucial genes. By analyzing interactions among these genes, researchers identified new potential targets for cancer therapy.