The current foci of diabetic neuropathy research are oxidative stress, advanced glycation end products (AGEs), protein kinase C (PKC), and the polyol pathway.

Cite this: Protein Kinase C-β Gene Variants, Pathway Activation, and Enzastaurin Activity in Lung Cancer - Medscape - May 01, 2010. Abstract and Introduction Patients and Methods ...

Dip2 regulates PKC signalling through specific DAG acyl chain compositions—a crucial pathway, which emerged approximately 1.2 billion years ago, marking the advent of selective DAG-based signalling in ...

Xanthones can also influence protein kinase C (PKC) pathways, regulating ion channel activities on beta-cell membrane and subsequent insulin release.

(3) PMA experiments: Line 223-224: A major concern is related to the conclusion that "blood flow activates Notch in the cushion endocardium via the mTORC2-PKC signaling pathway". To make that claim, ...

Protein kinase C-ζ (PKC-ζ) is a serine/threonine kinase belonging to atypical protein kinase C (PKC) subfamily, and is activated by its phosphorylation. We and others have reported that PKC-ζ induced ...

In the present in silico research work, the presence of integral control in the protein kinase C ζ – insulin receptor substrate-1 (PKC ζ-IRS1) pathway is identified, verified mathematically and model ...

Thirdly, systemic inflammation activated the PKC/MEK/ERK and NF-κB signaling pathways in LID rats. Clo-lipos ameliorated the effect of peripheral LPS injection, improved behavioral dysfunction, ...

PKC, PKA, and PKG pathways control posttranslational regulation of receptor and channel proteins, and also have influences on gene expression.

Genetic analysis of PHAII has revealed a previously unrecognized pathway that regulates blood pressure and electrolyte homeostasis in the distal nephron. ... (AngII) via protein kinase C (PKC).