The complexity of cancer signaling and the resulting difficulties ... In addition, mutations are frequently detected in proteins such as p53, KRAS and APC (adenomatosis polyposis coli), which ...

Pancreatic cancer is a leading cause of cancer-related death, with a five-year survival rate of 13%. The high mortality is ...

Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.

This important study shows that nutrient stress emanating from the microenvironment induces metabolic vulnerabilities in pancreatic ductal adenocarcinoma (PDAC). Using a combination of cell-based and ...

During the past 20 years, the advent of neoadjuvant, primary, and adjuvant concurrent chemoradiotherapy has improved cancer care dramatically. Significant contributions have been made by ...

Tripathi, Sheema Khan, Murali M. Yallapu, Everardo Cobos, Subhash Chauhan. MUC13 expression renders radio-resistance in human colorectal cancer cells through NRF2 signaling pathway [abstract]. In: ...

They have an increased risk of dying from both liver diseases and common diseases such as cancer and cardiovascular ... Mother's High-Fat Diet Can Cause Liver Stress in Fetus Mar. 13, 2025 ...

Researchers at Hopkins have made strides in pancreatic cancer research, both in understanding age-related differences in ...

The University of Kentucky, Lexington, KY.

Figure 1: Representative images of the induction of autophagy and the outcome of its suppression. Figure 2: The role of autophagy in development and differentiation in mammals.