The network consists of cancer-related genes (as seed nodes) and edges capturing their interactions to transverse the ten important signaling ... the cell-cycle and p53 pathways in BLCA were ...

ROS activated the p53 signaling pathway and promoted the nuclear translocation ... Hdy-7 showed comparable cytotoxicity against five cancer cell lines, including Taxol resistant A549 Taxol cells.

"By using this technology, we can restore tumor suppressor gene expressions such as PTEN, P53, or tumor antigens ... focuses on signaling pathways in cancer stem cells, and using cellular and ...