For a limited group of cancer patients who have solid tumors in the stomach, rectum, esophagus and other organs, an ...

Elicio Therapeutics, Inc. (Nasdaq: ELTX, "Elicio Therapeutics" or "Elicio"), a clinical-stage biotechnology company developing a pipeline of novel immunotherapies ...

Elicio Therapeutics, Inc. (Nasdaq: ELTX, “Elicio Therapeutics” or “Elicio”), a clinical-stage biotechnology company ...

1Nuclear Dynamics and Cancer Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania. 2Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia ...

1Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania. 2The Melanoma and Skin Cancer Center, The Pennsylvania State University College of Medicine, ...

Scientists mapped genetic mutations in stomach lining cells and found early cancer signals and rare chromosome anomalies, suggesting a potential new mutagen. The study deepens understanding of how ...

Understanding your tumor biology is key to finding the right treatment for pancreatic cancer. Identifying mutations, or changes in a cell’s DNA, can help doctors understand how cancer might grow and ...

Along with the scientists at Peel Therapeutics, a company founded by Schiffman in 2015, Abegglen is working on translational strategies for applying elephant p53 to human health. In a poster ...

p53 inactivation via mutations or enhanced degradation by MDM2 is the most frequent alteration in human cancers, which underscores the key role of p53 in combating cancer. Reinstatement of p53 by ...

All the various tp53 and Trp53 clones used in cancer studies came from transformed cell lines; they all contained mutations. Once researchers redefined p53 as a tumor suppressor gene and generated ...