KAIST researchers have discovered that 'DEAD-box helicases 54 (DDX54)', a type of RNA-binding protein, is the master ...

Researchers have discovered that 'DEAD-box helicases 54 (DDX54)', a type of RNA-binding protein, is the master regulator that hinders the effectiveness of immunotherapy -- opening a new path for lung ...

Immune checkpoint inhibitors, a class of immunotherapies that help immune cells attack cancer more effectively, have ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

The purpose of this study was to develop a method of classifying cancers to specific diagnostic categories based on their gene expression signatures using artificial neural networks (ANNs).

Myc-tagged HEYL was cloned into a promoterless pcDNA3-hygro vector fragment. The final vector, pcDNA3-hygro-HEYL, was transfected into breast cancer cell line HS578T with tTA-IRES-Neo vector. After ...

Pathway analysis of their predicted targets revealed enrichment in several biological processes in agreement with ARDS pathophysiology, such as inflammation, immune cell activation, and fibrosis. By ...

In 2011 she moved to do her postdoc with Nicolas Tapon at the Cancer Research UK London Research Institute (now The Francis Crick Institute), where she worked on the regulation of tissue growth via ...