These insights from researchers could have major implications for diseases like cancer, where gene expression goes awry.

Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells, Cell (2019). Guanshi Wang, Jesse Hauver, Zachary Thomas, Seth A. Darst, Alexandros Pertsinidis.

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results from a combination of higher Pol II turnover and lower transcription ...