Model of cell cycle regulation and genome integrity protection by CHK1 in early mouse embryos. In wild‐type mouse embryous, active CHK1 (shown in purple) restrains CDK1 activity (gray) by promoting ...

An international research team led by the IPK Leibniz Institute has uncovered the molecular mechanisms governing the ...

Capricor's DMD therapy Deramiocel is under FDA Priority Review with no major issues flagged; PDUFA date set for August 31, ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the ...

Circadian regulation of the cell cycle progression generates a diurnal supply of newborn cells to replace those lost in organs and tissues. In this study, we analyzed circadian time-dependent changes ...

The cell cycle is a biological process requiring the interaction of multiple components to produce a new cell. How these processes synchronize with cell cycle progression, however, is currently ...

Disruptions in circadian rhythms contribute to tumor initiation and progression through multiple mechanisms. These include metabolic reprogramming, alterations in cell cycle regulation, and ...

GSPT2 (G1 to S phase transition protein 2) has emerged as a critical regulator of the cell cycle and has garnered increased attention for its role in tumor biology in recent years. This review ...

During organismal development, differential regulation of the cell cycle is critical to many cell biological processes, including cell migration, cell fate specification and differentiation. While the ...

The following is a summary of “Patient iPSC-derived neural progenitor cells display aberrant cell cycle control, p53, and DNA damage response protein expression in schizophrenia,” published in the ...

After losing volume between morning and evening, the brain resets overnight, starting the cycle again, the research shows. The study involved scanning a 26-year-old's brain 40 times in 30 days.

Later in each cycle, high CCO activity inhibits centrosome growth by suppressing the centrosomal recruitment and/or maintenance of centrosome proteins. Thus, in fly embryos, mitotic centrosome size ...