Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments ...

The UCLA advance opens the door to growing other vascularized organ models, including intestines and colons, providing ...

Nutrition scientists have been working to understand the relationship between type 2 diabetes and genes that express a ...

A study published in Cell Stem Cell reveals that some mutations in blood stem cells might help protect against late-onset ...

This article makes a valuable contribution to the field by uncovering a molecular mechanism for miRNA intracellular retention, mediated by the interaction of PCBP2, SYNCRIP, and specific miRNA motifs.

Another BCMA-targeted agent has arrived for the treatment of multiple myeloma. | After a delay, Regeneron’s BCMA-directed ...

On Wednesday, Biokin reported (PDF) positive topline results from a phase 3 trial of the ADC. The study enrolled patients ...

Methods We developed three key reagents to evaluate VIP for SARS-CoV-2: (i) we engineered standard laboratory mice to express human ACE2 via rAAV9 in vivo gene transfer, to allow in vivo assessment of ...

Superenhancers regulate the expression of genes that specify cell type-specific development, but little is known regarding their function and regulation in vivo. Here, we study the cytokines IL-2 and ...

LaVaute, T., Smith, S., Cooperman, S. et al. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice.

Venetoclax is a BCL2 homology 3 (BH3) mimetic oral drug that binds the anti-apoptotic protein BCL-2, displacing pro-apoptotic proteins to activate the intrinsic mitochondrial apoptotic response. 10 ...

Galatea Bio and Fabric Genomics, a GeneDx company, announced today a strategic collaboration to enhance genetic testing by incorporating both rare pathogenic variant analysis and polygenic risk ...