What is PolG? The rare genetic disease that ended a young prince's life "PolG disease has been described as really one of the most progressive forms of mitochondrial disease," said Philip Yeske.

PolG disease is a genetic disease caused by mutations that occur in the POLG gene in the mitochondria of a person's cell, according to the UMDF.

POLG mutations are the most common cause of inherited mitochondrial disorders, with around 300 mutations in POLG known to cause disease. Examples of POLG-related diseases include Alpers ...

Prince Frederik of Luxembourg (L). POLG Foundation. Tan worked directly with Frederik on the project, meeting with him several times before she wrote the film’s script.

The PolG Foundation specifies that PolG mitochondrial disease is "a genetic mitochondrial disorder that robs the body’s cells of energy," causing progressive multiple organ dysfunction and failure.

Prince Frederik of Luxembourg has died at the age of 22 from POLG mitochondrial disease, a rare genetic disorder that he was born with, his family announced.

Frederik was diagnosed with the disease at the age of 14 after enduring unexplained symptoms for years. Royal Family of Luxembourg/Instagram “The POLG Foundation, in only three short years, has ...

What does the POLG Foundation do? In its three year tenure, the foundation has provided $3.6 million of funding for four major research projects looking at the mechanisms of the disease and ...

A young European royal has died due to a rare genetic disorder at the age of 22. Prince Frederik of Luxembourg passed away from a rare mitochondrial condition affecting two of his POLG genes that ...

POLG Mitochondrial disease is a rare genetic disorder caused by mutations in the POLG gene, which can affect multiple organs, mainly the brain, muscles, liver and nerves, according to the United ...

PolG is one of many other rare disorders classified as mitochondrial diseases. Over 400 mitochondrial diseases, including PolG, have been identified, according to Yeske.