The pre-B-cell receptor (pre-BCR), which comprises two Igμ chains and two germline-encoded surrogate light chains (SLC) that are associated with the signalling subunits Igα and Igβ, is formed ...

demonstrating effects on pre-B-cell receptor signaling. In therapeutic targeting studies, we demonstrated antitumor effects of the IIIA4 mAb in EphA3-expressing leukemic xenografts and no ...

Anti-CD20 mAbs were originally created to treat B cell proliferative diseases such as non-Hodgkin's lymphoma and chronic ...

Development of B cells, white blood cells that make antibodies, follows a progression of stages: common lymphoid progenitors, pre-pro-B cells ... showed that Notch, a receptor in a highly ...

Abbreviation: BAFF-R = B-cell-activating factor receptor. Activated B cells in the circulation and brain. Activated B cells-including memory B cells and plasmablasts-from the circulation migrate ...

Therefore, when a B cell receptor encounters the nanoparticle immunogen ... and/or vaccinated against SARS-CoV-2," Wang says. "In pre-vaccinated mice, mosaic-7 COM is consistently giving the ...