Can We Reverse Aging? Scientists Uncover a Key “Zombie Cell” Pathway
New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...
Nature17d
Apoptosis and cancer: the genesis of a research field
The discovery of the Bcl-2 protein family, as well as p53 and its involvement in regulating apoptosis, and the CD95 (also known as FAS or APO1) pathway, led to an understanding of the molecular ...
Scientists aim to repair or replace p53 to combat cancer
For example, drugs can activate apoptosis or halt cell division in ways that mimic p53's normal function. Drugs like ABT-737 ...
EurekAlert!5d
The common hallmarks and interconnected pathways of aging, circadian rhythms, and cancer: implications for therapeutic strategies
A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery ...
Nature10y
Targeting apoptosis: selected anticancer strategies
Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...