What are the symptoms of NF1? Among the common signs of the condition are freckles or brownish spots called cafe-au-lait spots on the skin, presence of bumps on or under the skin, larger areas on ...

In cases where a diagnosis cannot be made based on the presence of physical symptoms, genetic testing for the NF1 gene mutation is currently available and may be appropriate for some families in order ...

However, sometimes a diagnosis of NF1 can’t be made definitively based only on physical signs and symptoms – such as in cases of very young children who have developed café-au-lait spots but no other ...

While the tumors are often benign, they can become cancerous over time and may cause a range of symptoms depending on where they are. For example, NF-1 can cause soft tissue and brain tumors that ...

“There are no treatments for many NF1 symptoms; current treatments for NF1 plexiform neurofibromas, such as surgery and MEK inhibitors, are helpful but come with their own set of trade ...