Investors had two reactions to Israel's broad attack on Iran late Thursday: They sold stocks broadly and bought crude oil and gold. Futures trading suggests the Standard & Poor's 500 Index will open down 52 points.

Global stocks slid and oil prices rose on Tuesday as fighting between Israel and Iran entered its fifth day, sowing fears of a broader regional conflict, while investors took in stride the Bank of Japan's decision to slow the pace of its bond tapering.

Asia stock markets were little changed on Monday, following Friday’s sharp sell-off on Wall Street amid escalating Middle East tensions and global economic concerns. Investors digested a batch of mixed Chinese economic data.