The Binding of Isaac, the video game, remains one of the best roguelike games of all time. Even if you haven’t played the game yourself, there’s a good chance you’d recognize its distinct ...

Unlocking characters with unique traits is crucial for success in The Binding of Isaac: Rebirth. Characters like Lazarus, Samson, and Magdalene offer varying benefits to players. Each character ...

The Binding of Isaac: Rebirth's long-awaited free online co-op mode finally has a release date. Creator Edmund McMillen ...

The Binding of Isaac: Game Boy Edition plans to be a mostly fully-featured demake of the original Binding of Isaac for the Nintendo Game Boy system. The Binding of Isaac IP and all of its characters ...

Surprise! It's Hell on Earth! It's a Deadly Sin Fingering a Coin Box! NEXT! all music is from The Binding of Isaac Rebirth And yes, WeirdVirusPorn is a thing, and without it this video wouldn't really ...

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The Binding of Isaac API is a project aiming to make available as much data about the Binding of Isaac game series as possible. The current release can be found at isaac.jamesmcfadden.co.uk/api/v1.

Unlock Mom's Knife by beating Satan with Isaac for a game-changing, penetrating knife. In The Binding of Isaac: Rebirth, players take Isaac on a dangerous journey through his mom's basement.