A key problem is the ability of glioma stem cells to regenerate tumors after treatment and resist conventional therapies, making them a primary reason for treatment failure. Recent discoveries ...

A progress report for a phase 1 trial of CLD-101 in recurrent glioma shows safety and feasibility at multiple intracerebral ...

Stem cell-like glioma cancer cells that share many characteristics with normal stem cells propel the lethal growth of brain cancers by promoting tumor blood vessel formation. Stem cell-like glioma ...

DelveInsight’s, “Glioma Pipeline Insight, 2025” report provides comprehensive insights about 180+ companies and 200+ pipeline ...

Malignant gliomas and medulloblastomas also exhibit heterogeneity at the cellular level, with subpopulations of tumour cells harbouring stem-like properties rendering them more resistant to therapy.

In an early-stage clinical trial, the therapy nearly doubled the expected survival time of young patients. Still, experts ...

a neural stem cell-based oncolytic virotherapy, in patients with recurrent high-grade glioma, a deadly and aggressive form of brain cancer. The Phase 1 trial is assessing the safety and ...

13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA ... promise in suppressing the self-renewing cancerous stem cells that challenge the present standards of care ...

Glioblastoma multiforme (GBM), commonly referred to as glioblastoma, is a malignant intracranial tumor derived from glial ...