The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated ...

or sometimes by switching off the gene altogether to see what happens if it doesn’t work (these are called knockout mice, and they’re a staple of medical lab research). In 2013, researchers in ...

Colossal Biosciences has announced the birth of the world’s first “woolly mouse”. The mouse has been genetically engineered ...

Colossal Biosciences announced it has genetically engineered the Colossal Woolly Mouse, which has a warm coat like the woolly mammoth.

Mayo Clinic's Precision Mouse Engineering Core in Minnesota can construct gene-targeted vectors for mice to assist researchers.

The pioneering research of UC Santa Cruz’s Upasna Sharma to determine how a father’s life experiences and environment can influence the health and wellbeing of his children moves forward with the ...

According to multiple research sites, mice are valuable tools for studying diseases in a laboratory setting. Here is what transgenic mice are.

By combining three editing technologies, Colossal engineered mice that express multiple mammoth-identified traits relevant to cold adaptation.

To address this gap, researchers conducted a series of experiments that identified the NACHT and WD repeat domain-containing protein 1 (Nwd1) gene and its role in liver pathogenesis. This ...