BCL6 is a regulator of SOCS2, so less BCL6 leads to less SOCS2. At normal levels, this allows BCL6 to control how much SOCS2 is expressed, and therefore, how much IGF1 is made.

A new study from the Salk Institute has revealed that a protein called BCL6 is key to maintaining healthy muscle mass. The experiments showed that mice with lower levels of BCL6 had significantly ...

Salk Institute researchers have identified that the protein BCL6 is key in maintaining muscle mass. Their research in mice revealed that boosting BCL6 levels restores muscle mass and strength ...

In contrast, after adding 20 mg/kg of monoclonal antibody against CD40 ligand to the regimen on days 0 and 2, we observed four thromboembolic complications in nine recipients. These included two ...

In a recent study, scientists have linked the protein BCL6 to the maintenance of muscle mass and further suggested that BCL6-boosting therapeutics could help GLP-1 users retain muscle while losing ...

Maintaining muscle mass is crucial for health, and researchers have identified the protein BCL6 as vital for this. Studies reveal GLP-1 medications for weight loss can cause muscle loss ...

That is notable, given that some earlier members of the CD40 class had serious safety issues that led to them being abandoned, particularly Biogen’s ruplizumab and Idec Pharma’s toralizumab ...

The CD40/CD40 ligand (CD40L) costimulatory system, which amplifies immune responses and can induce inflammation, is believed to have a role in skin manifestations of other autoimmune diseases ...

Get Instant Summarized Text (Gist) Increasing the protein BCL6 may help GLP-1 medication users retain muscle while losing fat. BCL6 is crucial for muscle maintenance, as shown in mice where its ...