When cortisol levels are low, the hypothalamus releases the corticotrophin-releasing hormone (CRH), which triggers the anterior pituitary gland to release the adrenocorticotropic hormone (ACTH).

A hypothetical model is shown for the activation of the central and local hypothalamic–pituitary–adrenal (CRH, ACTH, α-melanocyte-stimulating hormone and cortisol) system as well as sensory ...

who was found to have cyclical ACTH-dependent hypercortisolism following dynamic pituitary testing and serial late-night salivary cortisol measurements. The patient underwent endoscopic ...

Medically reviewed by Brian H. Wetchler, DO The adrenal glands are two small glands located on top of the kidneys. They ...