Several targeting approaches are in development. BCMA is preferentially expressed on plasma cells and other mature B cells in blood 5. These cells originate with B-lymphocyte progenitors that ...

When NSD2 was turned off, important markers like CD38 were reduced, and other genes normally silent in plasma cells were activated ... consequences of NSD2 over-expression in MM is not only ...

A new research paper was published in , Volume 16, on March 21, 2025, titled "NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma." ...