Typically, researchers injected mice with an antigen to provoke an immune response from B cells that secreted antibodies against the target antigen. However, researchers struggled to make large ...

The combination of different discovery technologies is of importance to obtain mAbs targeted against difficult antigens and rare functional epitopes. Advanced antibody lead optimization by ...

The investigators aim for the atlas to include hundreds of thousands - and potentially over 1 million - antibody-antigen pairs, compared to approximately 15,000 pairs currently available from ...

To identify human monoclonal antibodies (mAbs) against bacteria, most research has investigated antibodies that target a single antigen. However, it is important to obtain antibodies against ...

Candidate antigens displayed as ... not tuberculosis-positive individuals. Antibody signatures in serum from tuberculosis-positive subjects from Armenia versus ones recruited in Sweden showed ...