Palou and Chip Ganassi Racing continued their winning ways in 2025 by racing to victory in the Indy 500, marking Palou’s first career oval win. The remarkable Palou became the first driver since A.J. Foyt in 1979 to win five of the season’s first six races, and he has claimed three of the last four championships, including two in a row.

Pato O’Ward (+500 at DraftKings Sportsbook): O’Ward was narrowly edged out by Newgarden in the 2024 Indianapolis 500 and will look to close the deal this time. He has placed second twice in the last four races this season, but did not place in the top 10 in practice. Dixon will start third and is at +250 to finish first or second.

SportsLine's Steven Taranto reveals his picks and props for the 2025 Indianapolis 500 at Indianapolis Motor Speedway, where Pato O'Ward, Alex Palou, Scott Dixon and Robert Schwartzman are favorites